The premium silicone oil with an Xtra dose of elasticity.
Application
Siluron® 1000 / 2000 / Xtra / 5000 are colorless, homogeneous liquids made from highly purified polydimethylsiloxane. Siluron® 1000 / 2000 / Xtra / 5000 contain no biologically active components,
are chemically and physiologically inert, and non-toxic. These products are used in ophthalmic surgery as postoperative long-term endotamponades following the surgical treatment of severe retinal
detachments. They are also used as tamponades in macular hole surgery.
Composition
Contents per 10 ml syringe
100% polydimethylsiloxane
Density
940 – 980 kg/cm³ (at 35 °C ± 2 °C)
Properties and Benefits
Innovative molecular design for a new generation of silicone oils
Due to their special molecular structure, Siluron® Xtra and Siluron® 2000 demonstrate a high in vitro emulsification resistance compared to standard silicone oils. These two innovative oils are composed of a blend of extremely long molecular chains with viscosities around 2,500,000 mPas and short molecular chains with viscosities around 1,000 mPas.
This unique molecular design allows Siluron® Xtra and Siluron® 2000 to adapt their viscous behavior in response to the continuous shear forces present in the eye due to constant movement. The greater the applied shear force, the more viscous the silicone oil becomes—making it more resistant to emulsification. In contrast, conventional oils tend to decrease in viscosity over time when exposed to constant external forces, which increases their tendency to emulsify.
The new generation of silicone oils – Siluron® 2000 and Siluron® Xtra – stands out due to its significantly increased emulsification resistance. This is based on an intelligent blend of molecular chains of varying lengths, resulting in dynamic viscosity. Additionally, their good injectability through small incisions is another advantage of these innovative silicone oils.
High emulsification resistance
Good long-term biocompatibility
Excellent chemical purity
Literatur: Chan YK., Ng CO., Knox PC., Garvey MJ., Williams RL., Wong D.: Emulsification of silicone oil and eye movements; Invest Ophthalmol Vis Sci 2011; 52: 9721-9727